Primer on the Autonomic Nervous System 4th Edition

 Neurology/Neurosurgery  No Responses »
Dec 102023
 

Primer on the Autonomic Nervous System, Fourth Edition provides a concise and accessible overview of autonomic neuroscience for students, scientists, and clinicians. The book’s 142 chapters draw on the expertise of more than 215 basic scientists and clinicians who discuss key information on how the autonomic nervous system controls the body, particularly in response to stress. This new edition also focuses on the translational crossover between basic and clinical research. In addition to comprehensively covering all aspects of autonomic physiology and pathology, topics such as psychopharmacology decoding and modulating nerve function are also explored.

  • Provides concise and practical information on the autonomic nervous system
  • Discusses all aspects of autonomic physiology and pathology
  • Contains new content on psychopharmacology and modulating nerve function

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Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology, 2547) 3rd ed. 2022 Edition

 Pharmacology  No Responses »
Dec 102023
 

This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care.

Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.

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Receptor Binding Techniques (Methods in Molecular Biology, 897) 3rd ed. 2012 Edition

 Miscellaneous  No Responses »
Dec 102023
 

A broad definition of a receptor is a specialized protein on or in a cell that recognizes and binds a specific ligand  to undergo a conformational change, leading to a physiological response or change in cell function.  A ligand can be an endogenous neurotransmitter, hormone, paracrine/autocrine factor, or a synthetic drug that may function as an agonist or antagonist. The third edition of  Receptor Binding Techniques expands upon the methods and techniques used for studying receptors in silico, in vitro and in vivo. Comprehensive chapters describe how to use online resources for experimental research such as prediction of receptor-ligand interactions and mine the IUPHAR receptor database. Classical techniques of radioligand binding, quantitative autoradiography and their analyses are complemented by the use of  immunocytochemistry  for the cellular localization of receptor protein and hybridization to detect receptor mRNA.  Protocols using fluorescent labeled ligands are described to visualise receptors in living cells, their interaction with beta-arrestin to measure ligand-induced internalisation and  green fluorescent protein to study  trafficking. Non-radioactive, chemiluminescent cAMP and arrestin assays facilitate the identification of novel ‘biased agonists’. Detailed methods are provided for in vivo imaging of receptors using positron emission tomography (PET).

Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Receptor Binding Techniques, Third Edition, aids scientists in continuing to study receptor binding.

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Physics for Clinical Oncology (Radiotherapy in Practice) 2nd Edition

 Oncology  No Responses »
Dec 102023
 

Radiotherapy remains a major non-surgical treatment modality for malignant disease, and an understanding of how this treatment works is essential in ensuring optimum practice. Trainees in oncology learn about ionising radiation, but to understand it fully they must also understand the physics relevant to its use in therapy.


This book is written specifically for the oncology and radiation team, supporting clinical oncologists in their understanding of the science which underpins radiotherapy. It begins with basic concepts and then explores the principles and practice of physics as it relates to radiotherapy, including discussion of specific types of therapy.

Written by authors chosen for their expertise in in their respective fields, and aligned to the Royal College of Radiologists FRCR Curriculum in Oncology, this volume will provide an excellent source of information for trainee and practicing oncologists, and wider radiotherapy teams. This second edition has been fully updated to reflect advances in technology and the increased complexity in modern radiotherapy, including two new chapters on imaging and a new brachytherapy chapter.

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Surgery of the Craniovertebral Junction 2nd Edition

 Surgery  No Responses »
Dec 102023
 

The original and definitive reference on surgery of the craniovertebral junction, now in an updated second edition

The craniovertebral junction, with a significant range of pathologies and anatomical complexities, continues to be a challenging area for surgeons. This new edition of Surgery of the Craniovertebral Junction focuses on surgical decision making and technological advances in the treatment modalities for this region. Written and edited by senior surgeons at University Hospitals Case Medical Center in Cleveland, Ohio, and the world-renowned Barrow Neurological Institute in Phoenix, Arizona, this is a comprehensive text that spine and skull base surgeons will refer to often. A content-rich, interactive DVD containing cadaveric dissections, animations of surgical approaches and techniques, and a selection of short, narrated cases, is included with the book.

Key Features:

  • Contains new chapters on stereotactic radiosurgery, endovascular surgery, and endoscopic skull base techniques, ensuring that surgeons stay current
  • Includes an interactive DVD with high-quality, compelling videos on anatomy and surgical methods, providing readers with visuals to aid in interpretation of the text
  • Reflects the technological advances and innovative treatment modalities that have improved patient safety and efficacy rates for surgery involving this highly complex area
  • Covers both open and minimally invasive surgical methods, enabling surgeons to hone their skills in both areas

Surgery of the Craniovertebral Junction, Second Edition is the surgical resource every spine and skull base surgeon should have on their bookshelf.

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Oxford Textbook of Pediatric Pain 2nd Edition

 Pediatrics  No Responses »
Dec 102023
 

Our understanding of how pain in early life differs to that in maturity is continuing to increase and develop, using a combination of approaches from basic science, clinical science, and implementation science. The new edition of the Oxford Textbook of Pediatric Pain brings together an
international team of experts to provide an authoritative and comprehensive textbook on all aspects of pain in infants, children, and youth.

Divided into nine sections, the textbook analyses pain as a multifactorial problem to give the reader a comprehensive understanding of this challenging subject. Evidence-based chapters look in depth at topics ranging from the long-term effects of pain in children, to complementary therapy in
paediatric pain. The text addresses the knowledge-to-practice gap through individual and organizational implementation, and facilitation strategies. Case examples and perspective boxes are provided to aid learning and illustrate the application of knowledge.

Written by clinicians, educators, trainees, and researchers, hand selected by the Editors for their practical approach and expertise in specific subject areas, the new edition of the Oxford Textbook of Pediatric Pain is an essential reference text in the assessment and treatment of patients and
families in the field of paediatric pain.

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Receptor Biology (No Longer Used) 1st Edition

 Miscellaneous  No Responses »
Dec 092023
 

This book is geared to every student in biology, pharmacy and medicine who needs to become familiar with receptor mediated signaling. The text starts with explaining some basics in membrane biochemistry, hormone biology and the concept of receptor based signaling as the main form of communication between cells and of cells with the environment. It goes on covering each receptor superfamily in detail including their structure and evolutionary context. The last part focusses exclusively on examples where thorough knowledge of receptors is critical: pharmaceutical research, developmental biology, neurobiology and evolutionary biology. Richly illustrated, the book is perfectly suited for all courses covering receptor based signaling, regardless whether they are part of the biology, medicine or pharmacology program.

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Normal Findings in Radiography 1st Edition

 Radiology  No Responses »
Dec 092023
 

This book deals with a subject that is seemingly trivial: normal findings in radiology. However, the normal is also the frequent, but not always the simple. Every radiologist has experienced difficulties in the systematics of imaging and with phrasing the diagnosis. This book is intended to answer three questions:

  • How should the diagnosis be phrased?
  • Which general scheme can I use to evaluate an image; how can I check for the degree of normality?
  • Which data allow me to evidence normality, and what measurements should be taken?

In spite of the introducion of digital X-ray imaging, the interpretation of conventional X-rays has not basically changed during the past ten years, which is evidenced by the development of this book. Since its first publication in 1987, it has gone through several unchanged reprints. In the 2nd German edition the text has hardly been changed; however, several new images have been added.

The method of making findings and the systematic method of interpreting images are still relevant today. Consequently, the strict and systematic organization of the book was left unchanged. The new layout leads to a clearer accessibility of the material for the reader.

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Pocket Atlas of Sectional Anatomy, Computed Tomography and Magnetic Resonance Imaging, Volume 3: Spine, Extremities, Joints 3rd Edition

 Anatomy  No Responses »
Dec 092023
 

Renowned for its superb illustrations and highly practical information, the third edition of this classic reference reflects the very latest in state-of-the-art imaging technology. Together with Volumes 1 and 2, this compact and portable book provides a highly specialized navigational tool for clinicians seeking to master the ability to recognize anatomical structures and accurately interpret CT and MR images.

Highlights of Volume 3:

  • New CT and MR images of the highest quality
  • Didactic organization using two-page units, with radiographs on one page and full-color illustrations on the next
  • Concise, easy-to-read labeling on all figures
  • Color-coded, schematic diagrams that indicate the level of each section
  • Sectional enlargements for detailed classification of the anatomical structure

Comprehensive, compact, and portable, this popular book is ideal for use in both the classroom and clinical setting.

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Pocket Atlas of Sectional Anatomy, Computed Tomography and Magnetic Resonance Imaing, Vol. 1: Head and Neck 3rd Edition

 Anatomy  No Responses »
Dec 092023
 

Renowned for its superb illustrations and highly practical information, the third edition of this classic reference reflects the very latest in state-of-the-art imaging technology. Together with Volumes 2 and 3, this compact and portable book provides a highly specialized navigational tool for clinicians seeking to master the ability to recognize anatomical structures and accurately interpret CT and MR images.

Features:

  • New CT and MR images of the highest quality
  • Didactic organization using two-page units, with radiographs on one page and full-color illustrations on the next
  • Concise, easy-to-read labeling on all figures
  • Color-coded, schematic diagrams that indicate the level of each section
  • Sectional enlargements for detailed classification of the anatomical structure

Comprehensive, compact, and portable, this book is ideal for use in both the classroom and clinical setting.

Volume II: Thorax, Heart, Abdomen, and Pelvis

Volume III: Spine, Extremities, Joints

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