The new mechanistic philosophy is divided into two largely disconnected projects. One deals with a metaphysical inquiry into how mechanisms relate to issues such as causation, capacities and levels of organization, while the other deals with epistemic issues related to the discovery of mechanisms and the intelligibility of mechanistic representations. Tudor Baetu explores and explains these projects, and shows how the gap between them can be bridged. His proposed account is compatible both with the assumptions and practices of experimental design in biological research, and with scientifically accepted interpretations of experimental results.
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Fully reviewed and revised for its second edition, the Oxford Handbook of Infectious Diseases and Microbiology maintains its position as the must-have guide to all aspects of infectious diseases and microbiology. Reflecting the current approach to joint postgraduate training programmes, the handbook takes an integrated approach to both subjects. It covers the basic principles of bacteriology and virology, along with specific guidance on individual diseases and conditions, all in the accessible Oxford Handbook style.
Selected as a Doody’s Core Title for 2021!
Fundamentals of Microbiology, Twelfth Edition is designed for the introductory microbiology course with an emphasis on the health sciences. It consolidates the important concepts and ideas necessary for mastery by students entering the health care field as a nurse or other allied health professional. Over many editions of Fundamentals of Microbiology, the textbook has reflected flexibility by evolving in response to the rapidly changing field of microbiology and the changing learning needs of students. The Twelfth Edition has been updated with the latest scientific and education research written with a global perspective on microbiology and infectious disease. Along with these revisions, the visual aspects of the text have been improved to make the understanding of difficult complex concepts more approachable and the figures more engaging. This the first textbook to include all the fundamental microbiological disease aspects of COVID-19 in context with chapter key concepts.
This volume provides detailed methods and key approaches used to mechanistically study DNA damage, as well as the factors involved in the damage response. Chapters guide readers through proteomics and biophysical approaches, analyzing protein function, quantifying DNA replication dynamics and nucleic acid base damage, as well as biochemical reconstitution of key pathways involved in DNA repair. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
