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The use of MATLAB® in clinical Medical Physics is continuously increasing, thanks to new technologies and developments in the field. However, there is a lack of practical guidance for students, researchers, and medical professionals on how to incorporate it into their work.

Focusing on the areas of diagnostic Nuclear Medicine and Radiation Oncology Imaging, this book provides a comprehensive treatment of the use of MATLAB in clinical Medical Physics, in Nuclear Medicine. It is an invaluable guide for medical physicists and researchers, in addition to postgraduates in medical physics or biomedical engineering, preparing for a career in the field.

In the field of Nuclear Medicine, MATLAB enables quantitative analysis and the visualization of nuclear medical images of several modalities, such as Single Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), or a hybrid system where a Computed Tomography system is incorporated into a SPECT or PET system or similarly, a Magnetic Resonance Imaging system (MRI) into a SPECT or PET system. Through a high-performance interactive software, MATLAB also allows matrix computation, simulation, quantitative analysis, image processing, and algorithm implementation.

MATLAB can provide medical physicists with the necessary tools for analyzing and visualizing medical images. It is useful in creating imaging algorithms for diagnostic and therapeutic purposes, solving problems of image reconstruction, processing, and calculating absorbed doses with accuracy. An important feature of this application of MATLAB is that the results are completely reliable and are not dependent on any specific γ-cameras and workstations.

The use of MATLAB algorithms can greatly assist in the exploration of the anatomy and functions of the human body, offering accurate and precise results in Nuclear Medicine studies.

KEY FEATURES

• • Presents a practical, case-based approach whilst remaining accessible to students

• • Contains chapter contributions from subject area specialists across the field

• • Includes real clinical problems and examples, with worked through solutions

Maria Lyra Georgosopoulou, PhD, is a Medical Physicist and Associate Professor at the National and Kapodistrian University of Athens, Greece.

Photo credit: The Antikythera Mechanism is the world’s oldest known analog computer. It consisted of many wheels and discs that could be placed onto the mechanism for calculations. It is possible that the first algorithms and analog calculations in mathematics were implemented with this mechanism, invented in the early first centuries BC. It has been selected for the cover to demonstrate the importance of calculations in science.

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Recent advances in the field of nuclear medicine (NM) are expanding the role and responsibilities of the nuclear medicine technologist (NMT) to include more complex and detailed tasks. New technologies are making the diagnosis, management, and treatment of illnesses more sensitive, more specific, more accurate, and ultimately safer for both the patient and the technologist.

Radiation Safety in Nuclear Medicine, Second Edition provides the latest technological advances and expanded responsibilities of today’s NMT while laying a solid foundation for understanding the basic physics behind the technology. As with the original, this edition teaches the units of radioactivity, exposure, and dosimetry, along with the principles of instrumentation needed for detection and measurement. Focusing on the issues of safety, this volume devotes considerable attention to the science and practice of safety techniques and includes information on rules and regulations.

In keeping with the expanding nature of the field, the second edition incorporates many updates and additions such as,

• Recent modifications to the U.S. Code of Federal Regulations specific to the use of radiopharmaceuticals in medicine
• The growing popularity of metabolic imaging with positron emissions tomography (PET)
• The benefits of merging two modalities, namely, the images of PET and computerized tomography (CT) into one short scanning procedure
• The new role of therapeutic radiopharmaceuticals that use molecular targeting as a method of localization

Providing a basic understanding of nuclear medicine, its scientific basis, diagnostic and therapeutic applications, safety practices and regulations, and future directions, Radiation Safety in Nuclear Medicine, Second Edition is the comprehensive reference for technologists, students, researchers, and other professionals in the Nuclear Medicine.

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This book volume provides in depth coverage of the nucleic acid field and aims to represent a broad diversity of the methodologies and a wide range of nucleic-acid-related topics within the fields of molecular biology and biomedicine. Chapters are divided in three sections detailing in vitro detection, nanotechnology and imaging, biomedical applications, and big data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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