Aug 182022
 

Explore the past, present, and future of cancer cytogenetics

In Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs. Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients. The book also discusses how cytogenetics – the study of chromosomes – meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics.

The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders. From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process? How was information of this nature put to good use in the clinical management of cancer patients?

Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers:

  • A thorough introduction to ancient theories of disease, the advent of cellular pathology, and how a scientific interest in chromosomes developed
  • Comprehensive exploration of the conceptual importance of Theodor Boveri and his somatic mutation theory of cancer
  • A detailed chronological resume of cancer cytogenetic discoveries during the 20th century
  • In-depth discussions of the role of chromosome abnormalities, oncogenes, and tumor suppressor genes in leukemias, lymphomas, and solid tumors, together with a survey of what chromosome analyses have revealed about the clonal evolution of neoplastic cell populations
  • A discussion of the importance of pathogenetic classifications of neoplastic diseases, the role chromosome abnormalities play in this context, and which technological breakthroughs can be expected in chromosome-oriented cancer research

Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics was written for everyone with a scientific or clinical interest in cancer, especially how acquired chromosome abnormalities lead to neoplastic transformation. The book teaches how cytogenetic analyses contribute to a better understanding of tumorigenesis, but also how the finding of specific chromosome aberrations can be crucial for the diagnosis, prognosis, and management of cancer patients.

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Global Epidemiology of Cancer: Diagnosis and Treatment 1st Edition

 Epidemiology, Oncology  Comments Off on Global Epidemiology of Cancer: Diagnosis and Treatment 1st Edition
Jul 212022
 

Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding the mortality and morbidity of cancer, and how we can prevent, diagnose, and treat the disease. Prevention of cancer is essential for saving lives. Prevalence and incidence of cancer are key factors that each government and population must be aware of. Advances in the study of cancer occur on a regular basis, and this book provides the latest insights about relationships between the disease and stem cells, tumorigenesis, molecular interactions, pathways, channels, and immunity.

 

Global Epidemiology of Cancer: Diagnosis and Treatment meets the needs of readers by providing current information about epidemiology (including molecular epidemiology), diagnosis, and treatment. Providing logical, step-by-step information on various cancers, this book consolidates all of the most up-to-date information and data from verified studies on all different types of cancers in the United States and throughout the world.

 

Chapters are presented so that each includes an overview, clinical manifestations, epidemiology, pathophysiology, etiology and risk factors, diagnosis, treatment, prevention, and prognosis.

 

Global Epidemiology of Cancer: Diagnosis and Treatment will be invaluable to graduate and postgraduate students, including medical students; nurses; physician assistants; residents in oncology; public health students and allied health students.

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Leukaemia Diagnosis 5th Edition

 Hematology, Oncology  Comments Off on Leukaemia Diagnosis 5th Edition
Jul 022022
 

From the bestselling author, Barbara J. Bain, the new edition of this practical reference on the principles of leukaemia diagnosis and classification has been fully updated, and incorporates the recently revised WHO classification.

Leukaemias are a very heterogeneous group of diseases, which differ from each other in aetiology, pathogenesis, prognosis and responsiveness to treatment. Accurate diagnosis and classification are vital for the identification of specific biological entities and underpin scientific advances in this field. The detailed characterization of haematological neoplasms is also essential for the optimal management of individual patients.

In this user-friendly guide, Professor Bain illustrates and explains how these many laboratory techniques are used for the diagnosis and classification of leukaemia and related disorders. Leukaemia Diagnosis, Fifth Edition will be highly valuable to trainee haematologists and laboratory scientists in haematology and related disciplines, and will also prove a useful reference source and teaching aid for those who already have expertise in this field. In addition, cytogeneticists and molecular geneticists will find that this book enhances their understanding of the relationship of their disciplines to the diagnosis, classification and monitoring of leukaemia and related disorders.

Essential reading for every haematologist and haematopathologist, Leukaemia Diagnosis, Fifth Edition features

  • Over 300 high quality full colour digital images of abnormal cells in leukaemia and lymphoma supplemented by histological, cytogenetic and immunophenotyping images
  • Recent information on cytogenetic and molecular genetic abnormalities in leukaemia
  • Updated information on the characteristic immunophenotypic characteristics of different categories of leukaemia

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Hematology-Oncology Clinical Questions 1st Edition

 Hematology, Oncology  Comments Off on Hematology-Oncology Clinical Questions 1st Edition
Jun 282022
 

A unique point-of-care guide to clinical hematology-oncology that answers the most frequently asked questionsHematology-Oncology Clinical Questions is the single-best resource for quickly converting the most current data and research into practical, diagnostic real-time solutions. This unique book answers more than 60 of the clinical hematology-oncology questions most commonly asked of the authors during consultation. The content flow simulates the consultation process: Question…Data…Synthesis…Solution. The initial chapters prepare you with essential background fundamentals of hematology-oncology. Subsequent chapters are divided into tumor type, beginning with solid tumor types, and then hematological malignancies. Each chapter includes:•Key Concepts•The Clinical Scenario•The Action Items•PearlsHematology-Oncology Clinical Questions will prove to be a powerful tool to help learners from all points of the clinical spectrum understand the basic concepts of caring for a cancer patient.

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Triple-negative Breast Cancer

 Oncology  Comments Off on Triple-negative Breast Cancer
Jun 222022
 

Triple-negative breast cancer (TNBC) represents a challenge clinically due to the lack of actionable targets coupled with an aggressive disease course and a worse prognosis compared to other breast cancer subtypes. This book covers aspects of TNBC ranging from epidemiology, biology, molecular classification, to currently available and potentially new therapeutic options for TNBC. This book contains a range of recommended resources, including recent reviews, schematic illustrations, and information for patients with TNBC. Individuals including researchers and educators, practitioners, pharmaceutical professionals, patients as well as their family members will find this book useful.

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Clinical Lymphatic Mapping in Gynecologic Cancers 2nd Edition

 Ob/Gynae, Oncology  Comments Off on Clinical Lymphatic Mapping in Gynecologic Cancers 2nd Edition
Jun 222022
 

Lymphatic mapping techniques have proven to be useful to the early detection and safe treatment of endometrial and cervical cancers; however, the techniques have much of value to offer for breast cancer also and particularly for vulvar cancer, where there has been an explosion of interest and research. In the new edition of Clinical Lymphatic Mapping of Gynecologic Cancers, the techniques are fully explained, with consideration of the latest developments and technologies.

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Oncology Board Review, Third Edition: Blueprint Study Guide and Q&A 3rd Edition

 Oncology  Comments Off on Oncology Board Review, Third Edition: Blueprint Study Guide and Q&A 3rd Edition
Jun 162022
 

Includes 6 months’ free ExamPrepConnect Digital Access with print purchase!

Now in its third edition, Oncology Board Review: Blueprint Study Guide and Q&A is designed to help you prepare for the American Board of Internal Medicine (ABIM) Medical Oncology Certification Exam. This comprehensive print + digital resource has been revised to include new treatment regimens, clinical guidelines, and other advancements impacting the field as well as updated board-style Q&A. Dedicated sections cover hematological malignancies and solid tumors with a templated chapter approach highlighting epidemiology, etiology and risk factors, diagnostic criteria, staging, signs and symptoms of the disease, prognostic factors, indications for treatment, and special considerations. Later sections address other topics found on the exam, including cancer genetics and tumor biology, supportive and palliative care, bone marrow transplantation, and biostatistics. With more than 240 practice questions, detailed rationales, and a convenient print + digital package, Oncology Board Review gives you the tools to study your way and the confidence to pass the first time!

Key Features:

  • Aligns with the latest ABIM Medical Oncology Certification Exam blueprint
  • Provides a comprehensive yet concise review of all hematologic malignancies and solid tumors
  • Covers anticancer therapies, clinical research methodology, survivorship and palliative care, and more areas found on the exam
  • Revised to include new treatment recommendations and FDA approvals
  • Includes end-of-chapter assessment questions with detailed rationales – a total of more than 240 questions throughout
  • Content available digitally via ExamPrepConnect for study on the go

ExamPrepConnect Features:

  • All the high-quality content from the book
  • Personalized study plan based on initial certification or MOC exam date
  • Ability to study by topic area to identify strengths and weaknesses
  • Timed practice test that simulates the test-taking environment
  • Discussion board to connect with Medical Oncology exam-prep community

See access details inside the book.

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Manual of Clinical Oncology 8th Edition

 Oncology  Comments Off on Manual of Clinical Oncology 8th Edition
Jun 152022
 

Concise, portable, and packed with essential information, Manual of Clinical Oncology is an indispensable resource for understanding basic science, clinical findings, and available technology as they relate to the diagnosis and management patients with cancer. The practical format provides high-yield content useful for participating in rounds ad making diagnostic and therapeutic decisions at the bedside. Edited by Dr. Bartosz Chmielowski and Dr. Mary Territo, both from UCLA School of Medicine, this eighth edition carries on the tradition of excellence set forth by longtime editor Dr. Dennis Casciato.
Key Features:

  • Incorporates recent major achievements in immunotherapies, biologics, and targeted therapies.
  • Features new chapters on the biology of cancer, immunotherapy, and cancer survivorship.
  • Contains numerous diagnostic and treatment algorithms, as well as content on complications, for assistance with clinical decision making.
  • Includes helpful appendices such as a glossary of cytogenetic nomenclature and combination chemotherapy regimens.

Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac.

Take advantage of these practical features that will improve your eBook experience:

  • The ability to download the eBook on multiple devices at one time — providing a seamless reading experience online or offline
  • Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks
  • Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design
  • The ability to highlight text and add notes with one click

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Neuro-Oncology for the Clinical Neurologist 1st Edition

 Neurology/Neurosurgery, Oncology  Comments Off on Neuro-Oncology for the Clinical Neurologist 1st Edition
Jun 152022
 

In the growing field of neuro-oncology, the past few years have witnessed rapid advances in tumor classification, treatment modalities, and the role of neurologists and neuro-oncologists. Neuro-Oncology for the Clinical Neurologist is a first-of-its-kind resource that focuses on patient-clinical scenarios relevant to the practicing neurologist—bringing you up to date with everything from basic principles and neuro-oncology imaging consults to neurologic complications of radiation, systemic, and immune-based therapies, and much more.

  • Focuses on the clinical management of patients typically encountered by neurologists and neurology trainees.
  • Provides clinically relevant updates in five key areas of neuro-oncology: primary CNS tumors, brain and leptomeningeal metastases, inherited tumor syndromes of the nervous system (e.g. neurofibromatosis), paraneoplastic and immune-mediated neurological complications of cancer, and neurological complications of cancer treatments.
  • Includes a summary of clinical pearls and a reference list of clinical cases. 
  • Anchors each chapter with patient cases and clinical scenarios, provides evidence-based discussion, and explains patient management.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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Advanced Skin Cancer: A Case-Based Approach

 Dermatology, Oncology  Comments Off on Advanced Skin Cancer: A Case-Based Approach
Jun 132022
 

Advanced skin cancer is one that has already metastasized beyond its primary origin, or one that has invaded underlying tissues such that surgical resection either is technically impossible or would lead to an unacceptable functional or cosmetic outcome. These skin cancers present a complex problem that requires the input of multiple specialties to delineate the best management plan. National guidelines utilize the best available data to guide management decisions. However, there is considerable leeway within the guidelines, enabling the ultimate care decision to be molded to best fit each individual patient. This book aims to provide instructional examples of patient cases where the input of the multidisciplinary team is critical in providing the most suitable care plan for the patient.

 

CONTENTS: Melanoma * Squamous Cell Carcinoma * Basal Cell Carcinoma * Cutaneous Lymphoma * Kaposi’s Sarcoma * Dermatofibrosarcoma Protuberans * Merkel Cell Carcinoma * Rare Cancer Presentations

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