This book covers scientific, clinical, and educational aspects of radiotheranostics in cancer control. Setting the framework, the first volume defines radiotheranostics and describes the history of radionuclide therapy and theranostics, and the biology of cancer. It examines the clinical applications of unconjugated radionuclides, such as ¹³¹I and ²²³Ra, and of radionuclide-conjugated cancer-specific vectors: peptides, small molecules, antibodies, and nanoparticles; introduces clinical trials and drug development; and reviews epidemiological studies and the adverse effects of radionuclide therapy – both radiation injuries and chemical toxicity. It presents the chemistry and physics of radionuclide production, discusses radioactivity measurements and traceability, and addresses important instrumentation aspects: calibration, quantitative imaging, and quality control. Volume I concludes with guidance on the education, training, and competence of a radiotheranostic multidisciplinary team and summarizes the principal physics characteristics of theranostics today – including many to be expanded in the second volume – while offering a glimpse into tomorrow. This volume provides the foundations for the more advanced second volume, which explores dosimetric and radiation safety, aiming to empower medical physicists and demonstrate to the cancer community how to improve cancer control and yield increased patient survival times.It will be a valuable reference for medical and health physicists with basic knowledge of nuclear medicine.
Key Features
Provides a comprehensive introduction to the topic, presenting readers with thorough treatment in a cohesive two-volume book
Presents a rigorous approach while remaining accessible to students and trainees in the field
Contains consistent and extensive references to allow readers to delve deeper into the subject
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Making a correct diagnosis is one of the key aspects of every medical student’s and junior doctor’s clinical training, and problem-based learning is now widely used to focus on the causes behind the presentation of a clinical feature. The Fourth Edition of this best-selling book is packed full of information to help the reader move from a presenting problem to an accurate diagnosis.
This new edition includes updated material, better visual images, and many new photographs relating to decomposition, autopsy techniques, various injuries, violent asphyxial deaths, and snake and scorpion poisoning. Recent topics like the Protection of Children from Sexual Offences Act, 2012, and recent changes in the criminal law in relation to rape, sexual deviations, penetrating sexual assault, and acid attacks have been incorporated. Other topics of current importance like body farming, virtual autopsy, narcoanalysis, hair dye poisoning, new plant poisons like brasinolide, and khat abuse have been added.
Now in its fifth edition, the Oxford Handbook of Emergency Medicine is the essential rapid-reference guide to emergency medicine for everyone from junior doctors to specialist registrars, nurse practitioners, and paramedics. New and improved, the Handbook has been thoroughly revised
Encyclopedia of Infection and Immunity, Four Volume Set provides new insights into the interactions between bacteria, fungi, parasites and their hosts. Specific areas of interest include host cellular and immune response to microbes, molecular mechanisms of action of beneficial microbes or host-associated microbial communities, microbial pathogenesis, virulence factors, experimental models of infection, host resistance or susceptibility, and the generation of innate and adaptive immune responses. Comprised of over 200 chapters written and edited by leading experts in the field, this book will serve as a key resource for students, researchers, academics and industry practitioners in the fields of microbiology, immunology, and infectious diseases.
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Through ten outstanding editions, Werner & Ingbar’s The Thyroid: A Fundamental and Clinical Text has been the go-to reference for the most comprehensive coverage of the thyroid, including anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders. Now in full color throughout, the 11th Edition of this award-winning text remains the clinician’s preferred source of authoritative information on the thyroid—an essential resource for all endocrinologists and thyroid surgeons.Includes thorough updates and new content throughout the text, especially on thyroid cytopathology, thyroid imaging, and targeted therapy of thyroid cancer as well as a new full-color format.Covers all aspects of the thyroid, including thyroid hormone synthesis and secretion, thyroid function, and disorders such as thyrotoxicosis, hypothyroidism, and cancer.Discusses surgical management of thyroid cancer, thyroid disruptors, thyroid hormone analogs, thyroid dysfunction’s effects on other organ systems, the aging thyroid, subclinical hypothyroidism and hyperthyroidism, and thyroid disease in pregnancy.Features insights from international experts, including new editor Dr. Peter Kopp of Northwestern University’s Feinberg School of Medicine.Enrich Your Ebook Reading ExperienceRead directly on your preferred device(s), such as computer, tablet, or smartphone.Easily convert to audiobook, powering your content with natural language text-to-speech.
Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed.