Now in its sixth edition, the Handbook of Drugs in Intensive Care is the essential guide to using drugs safely and effectively in the intensive care setting. The book is split into two sections: an A-Z guide to the drugs available, and concise notes on the key topics and situations faced on a daily basis. The A-Z section provides succinct information on each drug including uses, limitations, administration directions and adverse effects. The second section details practice guidelines such as insulin therapy, Parkinson’s disease therapy when nil-by-mouth, and drug dosing in renal failure. This revised edition includes seventeen new drug monographs and covers several new topics, including blood glucose management. A colour chart showing drug compatibility for intravenous administration is included at the back of the book. Presented in a concise, compact format, this book is an invaluable resource for doctors, nurses, pharmacists and other healthcare professionals caring for critically ill patients.
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This Element is an introduction to the metaphysics of biology, a very general account of the nature of the living world. The first part of the Element addresses more traditionally philosophical questions – whether biological systems are reducible to the properties of their physical parts, causation and laws of nature, substantialist and processualist accounts of life, and the nature of biological kinds. The second half will offer an understanding of important biological entities, drawing on the earlier discussions. This division should not be taken too seriously, however: the topics in both parts are deeply interconnected. Although this does not claim to be a scientific work, it does aim to be firmly grounded in our best scientific knowledge; it is an exercise in naturalistic metaphysics. Its most distinctive feature is that argues throughout for a view of living systems as processes rather than things or, in the technical philosophical sense, substances.
Recent interest in the evolution of the social contract is extended by providing a throughly naturalistic, evolutionary account of the biological underpinnings of a social contract theory of morality. This social contract theory of morality (contractevolism) provides an evolutionary justification of the primacy of a moral principle of maximisation of the opportunities for evolutionary reproductive success (ERS), where maximising opportunities does not entail an obligation on individuals to choose to maximise their ERS. From that primary principle, the moral principles of inclusion, individual sovereignty (liberty) and equality can be derived. The implications of these principles, within contractevolism, are explored through an examination of patriarchy, individual sovereignty and copulatory choices, and overpopulation and extinction. Contractevolism is grounded in evolutionary dynamics that resulted in humans and human societies. The most important behavioural consequences of evolution to contractevolism are reciprocity, cooperation, empathy, and the most important cognitive consequences are reason and behavioural modification.
Current knowledge of the genetic, epigenetic, behavioural and symbolic systems of inheritance requires a revision and extension of the mid-twentieth-century, gene-based, ‘Modern Synthesis’ version of Darwinian evolutionary theory. We present the case for this by first outlining the history that led to the neo-Darwinian view of evolution. In the second section we describe and compare different types of inheritance, and in the third discuss the implications of a broad view of heredity for various aspects of evolutionary theory. We end with an examination of the philosophical and conceptual ramifications of evolutionary thinking that incorporates multiple inheritance systems.
The new mechanistic philosophy is divided into two largely disconnected projects. One deals with a metaphysical inquiry into how mechanisms relate to issues such as causation, capacities and levels of organization, while the other deals with epistemic issues related to the discovery of mechanisms and the intelligibility of mechanistic representations. Tudor Baetu explores and explains these projects, and shows how the gap between them can be bridged. His proposed account is compatible both with the assumptions and practices of experimental design in biological research, and with scientifically accepted interpretations of experimental results.
Male factor infertility is a common problem in reproductive medicine and can have a significant effect of the outcome of IVF treatment. This comprehensive book covers the diagnosis and treatment of male factor infertility in depth. It opens with a section on the basic science underlying the production of male gametes. There is then a major section on diagnosis that will prove very useful to a wide range of andrologists, endocrinologists, and REIs faced with unpicking the problems facing infertile couples. The final section addresses management of the subfertile male, including endocrinologic, surgical, and ART interventions. The book is authored by a prestigious, international team of contributors.
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