May 162024
 

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. A very special event the Nobel Minisymposium, “Molecular Oncology – From Bench to Bedside,” held at the Karolinska Instituet, in Stockholm, Sweden, was marked the celebration of George and Eva Klein’s combined 160th birthday. To honor this occasion, this 2nd of two volumes brings together contributions by their former students, colleagues and collaborators of the past fifty years into a volume of Advances in Cancer Research dedicated to George and Eva. Over a decade ago, a subdivision of ACR called “Foundations in Cancer Research” was initiated and the tributes honoring the Kleins’ bodies of work presented at the minisymposium are especially appropriate for the series.

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Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs (Paperback) – Highly Rated Pharmacology Book 1st Edition

 Oncology, Pharmacology  Comments Off on Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs (Paperback) – Highly Rated Pharmacology Book 1st Edition
Apr 032024
 

Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs provides a one-stop guide to the essential basic and clinical science of all the effective, life-prolonging drug therapies in oncology. From traditional cytotoxic agents to targeted genomic, epigenomic, hormonal, and immunotherapeutic agents, this pharmacology book covers the staggering advances in cancer pharmacology that are propelling new standards of care for common and uncommon malignancies.

Beautifully illustrated throughout, each chapter in this cancer pharmacology guide contains visually engaging figures detailing the tumor microenvironment, chemical structures of agents, pharmacodynamics, pharmacokinetics, pharmacogenomic, and molecular properties of the various agents, and their mechanisms of action. As the first illustrated book of its kind, this highly visual text uses a uniform approach to each cancer drug class and agent presented in the book, and covers alkylating agents, antimetabolites, antimitotics, epigenetic modulators, hormonal agents, targeted therapies, monoclonal antibodies, immunotherapeutic agents, and much more.

Flow diagrams, clinical tables, and bulleted text further explain important information pertaining to each cancer drug class including their indications, mechanisms of action, potential adverse reactions, dosing and dose adjustments, and safety monitoring. Organized in an easy-to-digest format and replete with detailed images, clinical pearls, and end of chapter Q&As, this evidence-based reference presents all major classes, agents, targets, and approaches to oncology pharmacotherapy.

Key Features:
Includes visual depictions of chemical structures, pharmacokinetics, pharmacodynamics, and pharmacogenomics associated with each class of agents
Describes how chemotherapy, targeted therapy, immunotherapy, hormonal therapy, work and why they are expected to work adjuvantly, neoadjuvantly, and in combination with other modalities
Over 135 highly stylized images and numerous comprehensive tables
Covers challenges related to drug development, drug approval and regulatory issues in relation to anticancer treatments
All chapters conclude with clinical pearls and detailed clinical Q&As with descriptive rationales
Purchase includes access to the ebook for use on most mobile devices or computers

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https://nitroflare.com/view/D726EE09460CA13/0826162037.pdf

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The Bethesda Handbook of Clinical Oncology 4th Edition

 Oncology  Comments Off on The Bethesda Handbook of Clinical Oncology 4th Edition
Mar 312024
 

The Bethesda Handbook of Clinical Oncology is a clear, concise and comprehensive reference book for the busy clinician to use in his or her daily patient encounters. It focuses less on etiology, pathophysiology, and epidemiology, and considerably more on practical clinical information. Cancer management information is presented in a reader-friendly format that offers a comprehensive review of each disease along with the most commonly used treatment regimens, including chemotherapy dosing and schedules.


Features:
Clear, concise, complete reference book for busy clinician for daily patient management
User-friendly formatting – tables, algorithms, charts, bullet points
Contributors all from NIH (or they trained there)
Great for board exams
Organized by body region

New to this edition:
Add a chapter on Cancer Genetics and expand the Basics of Genomics for practicing oncologists to include the clinically relevant molecular tests.
Major addition will be to add about 5 board review question and answers per chapter – more than 200 board review questions
New treatment regimens added to all appropriate chapters
New clinical trial data added on treatment
More chemotherapeutic agents added (including newer regimens and dosages)

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Pizzo & Poplack’s Pediatric Oncology 8th Edition

 Oncology, Pediatrics  Comments Off on Pizzo & Poplack’s Pediatric Oncology 8th Edition
Mar 282024
 

Comprehensive, authoritative, and up to date, Pizzo and Poplack’s Pediatric Oncology, 8th Edition, remains your most trusted source of information on the care and research of children with cancer. This award-winning text is the single most comprehensive reference on the biology and genetics of childhood cancer, its diagnosis and multimodal treatment, and long-term management. In the tradition of excellence established by Drs. Philip A. Pizzo and David G. Poplack, this 8th Edition keeps you fully informed while helping you collaborate more effectively with others on the cancer care team to enhance quality-of-life issues for patients and families.

  • Covers all aspects of the breadth and depth of childhood cancer, including basic science, diagnostic tools, principles of treatment, and clinical trials, as well as highly detailed, definitive coverage of each pediatric malignancy.
  • Includes updates to current treatment approaches based on the results of recently completed and published clinical research.
  • Contains new information on the biology of pediatric malignancies and strategies for the conduct of clinical trials that reflect the rapid pace of laboratory discovery.
  • Features chapters on palliative care and education, and covers supportive care in contexts such as emergencies, infectious disease, and nutrition.
  • Provides expert guidance on state-of-the-art, multidisciplinary care for children and families, including psychosocial aspects of care and perspectives from patients and parents.
  • Discusses the cooperative nature of pediatric oncology as a model for cancer research with information from cooperative clinical trial groups and consortia. 

Enrich Your eBook Reading Experience

  • Read directly on your preferred device(s), such as computer, tablet, or smartphone.
  • Easily convert to audiobook, powering your content with natural language text-to-speech.

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The Genetic Basis of Haematological Cancers 1st Edition

 Hematology, Oncology  Comments Off on The Genetic Basis of Haematological Cancers 1st Edition
Mar 152024
 

Written by a team of international experts, this book provides an authoritative overview and practical guide to the molecular biology and genetic basis of haematologic cancers including leukemia. Focusing on the importance of cytogenetics and related assays, both as diagnostic tools and as a basis for translational research, this is an invaluable guide for basic and clinical researchers with an interest in medical genetics and haemato-oncology.

The Genetic Basis of Haematological Cancers reviews the etiology and significance of genetic and epigenetic defects that occur in malignancies of the haematopoietic system. Some of these chromosomal and molecular aberrations are well established and already embedded in clinical management, while many others have only recently come to light as a result of advances in genomic technology and functional investigation. The book includes seven chapters written by clinical and academic leaders in the field, organised according to haematological malignancy sub-type. Each chapter includes a background on disease pathology and the genetic abnormalities most commonly associated with the condition. Authors present in-depth discussions outlining the biological significance of these lesions in pathogenesis and progression, and their use in diagnosis and monitoring response to therapy. The current or potential role of specific abnormalities as novel therapeutic targets is also discussed. There is also a full colour section containing original FISH, microarrays and immunostaining images. 

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Prostate Cancer: A Multidisciplinary Approach to Diagnosis and Management (Current Multidisciplinary Oncology) 1st Edition

 Oncology  Comments Off on Prostate Cancer: A Multidisciplinary Approach to Diagnosis and Management (Current Multidisciplinary Oncology) 1st Edition
Feb 212024
 

“This book admirably covers prostate cancer. It is written in an easily digestible manner for non-experts and emphasizes the importance of a team approach to treatment of patients with this disease.”–Doody’s Reviews

With an emphasis on multidisciplinary collaboration and decision-making, this practical resource reflects the extraordinary advances in the treatment of prostate cancer during the past five years. Approximately thirty international, leading-edge investigators describe the most current evidence-based approaches to prostate cancer treatment. The book provides a comprehensive view of the entire spectrum of prostate cancer management from initial screening through novel and experimental treatments that have the potential for a major impact on practice.

The book first reviews fundamental issues including epidemiology, screening, risk reduction, diagnosis and pathologic characterization, staging, and imaging. This includes strategies for improving the accuracy of PSA screening and an update on controversies surrounding the ISUP Modified Gleason Score. The book covers novel molecular and genotype profiling in prostate cancer, including morphometric and systems pathology. Detailed information is provided on radiographic imaging for diagnosis and staging. The treatment sections of the book correspond to the staging of disease. The treatment of localized disease addresses the range of multidisciplinary management options including a discussion of prostate cancer’s impact on the quality of life. A detailed review of multimodal therapies (medical, surgical, and radiologic) addresses the treatment of localized advanced disease, and coverage of advanced metastatic prostate cancer reviews current management options including a range of promising novel and experimental agents. The book also discusses counseling the high-risk patient. Several chapters incorporate models of care delivery, patient navigation for multidisciplinary care, genomic and risk assessment, and comparative effects of research in treatment decision-making. The book is designed as a management text for all health care professionals who provide care for prostate cancer patients as well as patients, families, and advocates. Extensive references offer opportunities for additional study.

Key Features:

  • Delineates a practical, concise approach to multidisciplinary management of prostate cancer
  • Provides a wide range of perspectives and expertise
  • Written and edited by an international, multidisciplinary team of prostate cancer specialists
  • Focuses on such key issues as special populations, screening controversies, patient counseling, and quality of life
  • Includes discussion of important emerging topics such as gene profiling and targeted therapies and comparative effectiveness data

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https://nitroflare.com/view/253B5EAC571BEC7/B00RKU1XQS.pdf

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Oncology: Board and Certification Review

 Oncology  Comments Off on Oncology: Board and Certification Review
Feb 122024
 

Get the best possible score on the Oncology Exam

This StatPearls review (8th edition) is designed to help you maximize your score on the Oncology Exam. Our questions target the American Board of Internal Medicine® and American Osteopathic Board of Internal Medicine® content outlines and match the question structure. We have 1st, 2nd, and 3rd order multiple choice questions and four detailed teaching points to help you rapidly prepare and achieve the best score possible. The questions are updated annually by 915 authors and 992 editors to improve your learning experience and to better match exam requirements. The single best way to improve your performance is to DO MORE QUESTIONS!

Know The American Board of Internal Medicine® and American Osteopathic Board of Internal Medicine® Exam

The exam is approximately 7 hours and consists of 300 questions with a pass rate of 85%. The exam covers Hematologic Neoplasms – 14%, Thoracic Cancer – 11%, Breast Cancer – 13%, Genitourinary Cancer – 12%, Gynecologic Cancer – 4%, Gastrointestinal Cancer – 13.5%, Skin Cancer, Sarcomas, and Unknown Primary Sit – 6%, Anticancer Therapeutics, Clinical Research Methodology, and Ethics – 9.5%, Palliative Care, Survivorship, and Communication – 11%, Head, Neck, Thyroid, and Central Nervous System Malignancies – 4%, and Genetics, Genomics, and Tumor Biology – 2% .

About StatPearls

Started as an academic teaching project in 2014, StatPearls has grown into the largest library of medical education in the world. More than 7,500 medical authors and editors have published more than 8,000 peer-reviewed PubMed indexed articles covering every specialty in healthcare. Along with these articles are more than 75,000 multiple choice questions with teaching points related to the content were created. These questions were then matched to the content outlines for every board and certification exam in healthcare, including our Oncology Exam review. This effort by thousands of sub-specialty experts has made StatPearls the most-comprehensive review resource available.

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Breast Cancer and Gynecologic Cancer Rehabilitation 1st Edition

 Oncology  Comments Off on Breast Cancer and Gynecologic Cancer Rehabilitation 1st Edition
Feb 012024
 

Breast Cancer and Gynecological Cancer Rehabilitation, edited by Adrian Cristian, MD, MHCM, provides today’s clinicians with a concise, accessible resource covering the holistic rehabilitation of breast cancer patients. Beginning with a review of epidemiology, genetics, and pathophysiology of breast cancer, it then covers clinical assessment and treatment options before providing comprehensive coverage of rehabilitation. Containing practical information, best practices, and the latest advances and research, this book is a valuable reference for physical medicine and rehabilitation physicians and residents, as well as occupational and physical therapists.

  • Provides a clear understanding of the current medical, surgical, and radiation treatments for breast cancer.

  • Covers the whole spectrum of breast cancer rehabilitation, including the role of physical and occupational therapy, treatment of anxiety and depression, pain syndromes, integrative care, nutritional rehabilitation, palliative care, and more.
  • Offers a timely and convenient resource written by leading experts in breast cancer and rehabilitation.

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https://nitroflare.com/view/8102B43B70DE7DA/0323721664.pdf

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Surgical Management of Advanced Pelvic Cancer 1st Edition

 Oncology  Comments Off on Surgical Management of Advanced Pelvic Cancer 1st Edition
Feb 012024
 

An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms 

Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: 

  • Surgical anatomy 
  • Operative approaches and exenterative techniques  
  • Reconstruction options  
  • Current evidence on survival and quality of life outcomes  

Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide. 

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https://nitroflare.com/view/6E39E2164FD79C7/B09KMBS2W7.pdf

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Cancer Biomarkers: Clinical Aspects and Laboratory Determination

 Oncology  Comments Off on Cancer Biomarkers: Clinical Aspects and Laboratory Determination
Jan 212024
 

Cancer Biomarkers: Clinical Aspects and Laboratory Determination provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence, focusing on emerging technologies, impacts on the field, and selected biomarkers currently used in clinical practice. The content highlights current laboratory tests used in the management of adult and pediatric cancer patients. In addition, it investigates the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies.

This title is a perfect reference for clinical pathologists, laboratory scientists, medical technologists, physicians specializing in oncology, internal medicine, family practice and transplant medicine, resident physicians, medical students, nurse practitioners and clinical chemists.

  • Provides insights into the overall complexity that the cancer patient presents and how laboratory tests are used in the management of care
  • Discusses current and new technologies applicable to cancer biomarker evaluation, including the use of non-traditional specimens like saliva, fluids and uterine lavage
  • Reviews current trends in liquid biopsy and cancer biomarkers
  • Provides a roadmap for bringing new technologies and markers from the bench to the bedside in the quest for finding the ideal tumor marker

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https://nitroflare.com/view/02F18B1B7E3906B/B0B3MGQNSV.pdf

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